![]() Laryngoscope 110: 198–203Īmbrosch P, Kron M, Fischer G, Brinck U (1995) Micrometastases in carcinoma of the upper aerodigestive tract: detection, risk of metastasizing, and prognostic value of depth of invasion. Surg Oncol Clin N Am 5: 33–41Īlex JC, Sasaki CT, Krag DN, Wenig B, Pyle PB (2000) Sentinel lymph node radiolocalization in head and neck squamous cell carcinoma. Careful clinical staging of the neck and thorough pathological evaluation of the sentinel nodes are necessary to avoid false-negative results.Īlex JC, Krag DN (1996) The gamma-probe-guided resection of radiolabeled primary lymph nodes. Our results support the sentinel node concept in head and neck cancer and a definition of the sentinel nodes as the three nodes with the highest activity. In four patients, a sentinel lymph node could not be localised. Three metastases were detected only after additional sectioning of the sentinel nodes. In 12 patients clinically occult metastases were found in the sentinel nodes. Of these 34 patients were free of metastatic disease in the sentinel nodes and in the neck specimens. In 46 patients sentinel nodes were detected. ![]() Pathological findings of sentinel nodes and corresponding neck specimens were compared. Sentinel nodes were localised using a gamma-probe in the setting of an elective neck dissection. In 50 patients with oral, pharyngeal or laryngeal carcinomas staged N0 up to 50 MBq technetium-99m colloid were injected peritumorally. The aim of the study was to assess the diagnostic value of the sentinel node method in patients suffering from squamous cell carcinoma of the upper aerodigestive tract.
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